Rise and Fall of Sufis in the Safavid period Viewpoints and judgments of Suifs about lords of power such as collision of Hatam Asam with Abbasid caliphate or Imam Mohammad Ghazzali with Sanjar Seljuk , have been surveyed firstly and then their Materialistic pacifism and Sovereignty seeking have been studied. Horoufi and Nourbakhshi sufis' action for reching power in Timurid period and the Sufi Sarbedarans' rulership in Khorasan raised lord of powers' pessimism against Sufis. Safavid kings made some difficulties for the Sufis after reaching the power. They let the dogmatists criticize the sufis vengefully and finally united with them and harmed the Sufis. Most of the works against Sufis and mysticism were written in Safavid period. In this research, the most important works are studied which includes Majlesi, Mohammad Taher Qomi and Hadighatol-Shia works.